It is not only a broad spectrum and the most efficacious pesticide of Avermectin kind, but also one of the lowest residue of this kind in milk. Trials show that the product with the concentration of 0.1mg/kg or 0.05mg/kg can efficaciously prevent seven kinds of nematodes parasitic on large intestine, small intestine and stomach of cattle and sheep. The efficacy is shown as 97% at least. Eprinomectin is used in beef and dairy cattle to control most G1nematodes and lungworms and also is effective against biting and sucking lice, chorioptic mange mites, cattle grubs, and horn files. Eprinomectin shows broad-spectrum activity against helminths and ectoparasites while leaving minimal residues in meat and milk. Eprinomectin is allowed to use to milking cows and there is no withdraw period.